Bone Marrow Transplant Match Testing

About This Treatment

Bone Marrow Transplant Match Testing, or Human Leukocyte Antigen (HLA) typing, is a blood test used to identify the best donor for a transplant recipient. A blood sample is obtained so that HLA proteins on the surface of white blood cells may be tested; if someone is histo-or tissue-compatible, there is a similarity of HLA antigens between the recipient and donor.

In the best-case scenario, a donor will have the exact HLA antigens as the recipient. For bone marrow transplantation, a near-perfect match is required whereas for kidney transplantation, a lesser match can result in a successful, functioning transplant. For bone marrow transplantation, the blood group of the donor is not important. In fact, after bone marrow transplantation, the patient will have the donor's blood type.

The HLA-Vascular Biology Laboratory at Franciscan Health Indianapolis is internationally recognized for its research and clinical testing expertise in the evolving relationship between disease and the presence of antiphospholipid antibodies.

• Molecular (DNA) HLA-A, -B, -C, -DR and -DQ low and high resolution typing
• Pre-transplant
• STR engraftment screen
• Post-transplant
• STR engraftment analyses
• PRA (panel reactive antibody) screen
• Flow cytometry crossmatch

The HLA-Vascular Biology Laboratory performs state-of-the-art histocompatibility testing for Indiana Blood Marrow Transplantation. Please contact the HLA-Vascular Biology Laboratory for information about how to order testing for bone marrow transplant recipients and donors.